CP Rail spokesman Breanne Feigel said the incident happened about 12:45 a.m. on a CP Rail line in a remote area, about 130 kilometres northwest of Sudbury.
There were no injuries to the crew and no public safety concerns, Feigel said.
The westbound train was carrying a mix of consumer goods, he added.
The cause of the derailment has not been identified.
CP Rail crews were heading to the scene early Saturday afternoon to assess the situation.
With files from The Canadian Press
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